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Candidate gene polymorphisms and risk of psoriasis: A pilot study.
Villarreal-Martínez A, Gallardo-Blanco H, Cerda-Flores R, Torres-Muñoz I, Gómez-Flores M, Salas-Alanís J, Ocampo-Candiani J, Martínez-Garza L. Villarreal-Martínez A, et al. Exp Ther Med. 2016 Apr;11(4):1217-1222. doi: 10.3892/etm.2016.3066. Epub 2016 Feb 9. Exp Ther Med. 2016. PMID: 27073425 Free PMC article.
These SNPs, which were associated with psoriasis in previous studies, included the following genes: Major histocompatibility complex class I-C (HLA-C), interleukin (IL)-12B, IL-23R, IL-23A, IL-28RA, tumor necrosis factor (TNF)-alpha, ring finger protein-114 (RNF1 …
These SNPs, which were associated with psoriasis in previous studies, included the following genes: Major histocompatibility complex class I …
Fine mapping of eight psoriasis susceptibility loci.
Das S, Stuart PE, Ding J, Tejasvi T, Li Y, Tsoi LC, Chandran V, Fischer J, Helms C, Duffin KC, Voorhees JJ, Bowcock AM, Krueger GG, Lathrop GM, Nair RP, Rahman P, Abecasis GR, Gladman D, Elder JT. Das S, et al. Eur J Hum Genet. 2015 Jun;23(6):844-53. doi: 10.1038/ejhg.2014.172. Epub 2014 Sep 3. Eur J Hum Genet. 2015. PMID: 25182136 Free PMC article.
After our first psoriasis genome-wide association study, we designed a custom genotyping array to fine-map eight genome-wide significant susceptibility loci known at that time (IL23R, IL13, IL12B, TNIP1, MHC, TNFAIP3, IL23A and RNF114) enabling genotyping of 2269 single-nu …
After our first psoriasis genome-wide association study, we designed a custom genotyping array to fine-map eight genome-wide significant sus …
Identification of loci associated with late-onset psoriasis using dense genotyping of immune-related regions.
Hébert HL, Bowes J, Smith RL, Flynn E, Parslew R, Alsharqi A, McHugh NJ, Barker JN, Griffiths CE, Barton A, Warren RB. Hébert HL, et al. Br J Dermatol. 2015 Apr;172(4):933-9. doi: 10.1111/bjd.13340. Epub 2015 Feb 5. Br J Dermatol. 2015. PMID: 25124732
Imputation using SNP2HLA and stepwise logistic regression analysis was performed for markers spanning the human leucocyte antigen gene region. RESULTS: Two loci (HLA-C and IL12B) previously associated with early-onset psoriasis showed significant association at a ge …
Imputation using SNP2HLA and stepwise logistic regression analysis was performed for markers spanning the human leucocyte antigen gene regio …